Polysorbate 80

Cosmetic Grade · Food Grade · Pharma Grade — Bulk supply across India & International Markets

What is Polysorbate 80?

Polysorbate 80, commercially known as Tween 80, is a non-ionic surfactant and emulsifier produced by the ethoxylation of sorbitan monooleate, derived from oleic acid. It is a pale yellow, oily liquid with an HLB value of 15, giving it strong oil-in-water emulsifying capability. It is one of the most extensively used and well-characterised surfactants in the pharmaceutical, food, and cosmetic industries, with applications ranging from everyday food products to advanced vaccine formulations.

Polychem Industries supplies Polysorbate 80 in cosmetic, food, and pharmaceutical grades to a wide range of manufacturers across India and internationally, including food and beverage companies, cosmetic formulators, and pharmaceutical and biotechnology companies. Its broad regulatory approval and extensive safety data make it a foundational ingredient across regulated industries.

Available Grades

GradeFormPurityStandardApplications
Cosmetic / Food / Pharma GradePale yellow viscous liquid99%+ active contentCosmetic / FSSAI / USP / Ph. Eur.Cosmetics, food emulsification, pharmaceuticals, vaccine adjuvants

Applications & Uses

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Food & Ice Cream Emulsification

Approved as a food additive (E433), Polysorbate 80 is one of the most widely used emulsifiers in ice cream and frozen desserts, improving texture, preventing ice crystal formation, and improving whip and overrun in frozen dessert manufacturing.

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Pharmaceutical Formulations & Vaccines

A critical excipient in pharmaceutical and biotechnology formulations, used to stabilise proteins, emulsify oil-based components, and as an adjuvant component in certain vaccine formulations, helping maintain product stability and bioavailability.

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Cosmetics & Personal Care

Used as an emulsifier and solubiliser in lotions, creams, hair conditioners, and cleansing products, helping disperse oils and active ingredients uniformly throughout water-based formulations.

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Salad Dressings & Sauces

Used in salad dressings, sauces, and condiments as an emulsifier to maintain a stable, uniform mixture of oil and water-based ingredients, preventing separation during storage and shelf display.

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Bakery Products

Used in baked goods including cakes, bread, and pastries to improve dough conditioning, crumb structure, and shelf life by emulsifying fats uniformly throughout the batter or dough.

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Laboratory & Biotechnology

Used extensively in laboratory and biotechnology applications including cell culture media, protein stabilisation, and as a component in diagnostic test kits due to its compatibility with biological systems.

Technical Specifications

Polysorbate 80 — Key Properties

Chemical FormulaC64H124O26 (approx.)
CAS Number9005-65-6
Molecular Weight~1310 g/mol (average)
AppearancePale yellow to amber viscous liquid/oily liquid
Purity99%+ active content
HLB Value15.0 (hydrophilic)
Density / Bulk Density1.06–1.09 g/cm3 at 20°C
pH6.0 – 8.0 (5% solution)
Packaging Available25 kg / 50 kg drums / 200 L drums
StorageStore in cool, dry place away from direct sunlight. May thicken at low temperatures — gentle warming restores fluidity.

Why Source Polysorbate 80 from Polychem Industries?

  • Cosmetic, Food, and Pharma Grade available with full documentation
  • Pharma Grade meets USP / Ph. Eur. specifications
  • FSSAI compliant Food Grade supply with Certificate of Analysis
  • Reliable bulk supply for food, cosmetic and pharmaceutical manufacturers
  • Competitive pricing with consistent year-round availability
  • Export documentation experience for international shipments

Frequently Asked Questions

Why is Polysorbate 80 used in vaccines?
Polysorbate 80 is used in certain vaccine formulations as an emulsifier or stabiliser, helping to maintain the physical stability of the vaccine formulation, assist in the delivery of certain antigen components, and in some cases as part of adjuvant systems. Its use in vaccines is based on extensive safety and efficacy data accumulated over decades of pharmaceutical use.
What is the difference between Polysorbate 80 and Polysorbate 20?
Polysorbate 80 is derived from oleic acid (a longer-chain unsaturated fatty acid) while Polysorbate 20 is derived from lauric acid (a shorter-chain saturated fatty acid). Polysorbate 80 has a slightly lower HLB (15 vs 16.7) and is generally preferred for emulsifying heavier oils and in food and pharmaceutical emulsions, while Polysorbate 20 is often preferred for solubilising lighter oils, essential oils, and fragrances.
Is Polysorbate 80 the same across cosmetic, food, and pharma grades?
The base chemistry is the same, but the grades differ in their purity specifications, testing requirements, and documentation. Pharma Grade meets the strictest pharmacopoeia standards (USP/Ph. Eur.) including limits on peroxide value, heavy metals, and other impurities. Food Grade meets FSSAI and food safety standards. Cosmetic Grade meets cosmetic industry purity requirements. The appropriate grade should be selected based on your specific regulatory and application requirements.
Do you export Polysorbate 80 outside India?
Yes. We export to Bangladesh, Sri Lanka, Nepal, Bhutan, and South Africa with full export documentation. Contact us for export pricing and lead times.

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