Calcium Gluconate

Food Grade · Pharma Grade — Bulk supply across India & International Markets

What is Calcium Gluconate?

Calcium Gluconate is the calcium salt of gluconic acid, widely valued as a source of supplemental calcium due to its gentle action on the digestive system and good bioavailability compared to some other calcium salts. It is a white, odourless crystalline powder or granular material that is moderately soluble in water, making it suitable for both oral supplement formulations and, in pharmaceutical grade, for intravenous calcium replacement therapy.

Polychem Industries supplies Calcium Gluconate in food grade and pharmaceutical grade to nutritional supplement manufacturers, pharmaceutical companies, and food fortification companies across India and internationally. Its excellent tolerability, established safety profile, and effectiveness as a calcium source make it one of the most widely used calcium compounds in both food and medical applications.

Available Grades

GradeFormPurityStandardApplications
Food GradeWhite crystalline powder/granules99%+ (Food / Pharma Grade)FSSAI / FCC / E578Food fortification, nutritional supplements, calcium tablets
Pharma GradeWhite crystalline powder99%+USP / BP / IPInjectable calcium formulations, oral calcium supplements

Applications & Uses

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Calcium Supplements

Widely used in oral calcium supplement tablets and formulations due to its gentle gastrointestinal tolerance compared to some other calcium salts, making it suitable for individuals who may experience digestive discomfort with alternative calcium sources.

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Intravenous Calcium Therapy

Pharma Grade Calcium Gluconate is used in injectable formulations for the emergency treatment of hypocalcaemia (low blood calcium), cardiac arrhythmias related to electrolyte imbalances, and as an antidote in certain cases of magnesium toxicity or fluoride exposure.

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Food Fortification

Used to fortify food products including beverages, bakery items, and dairy alternatives with additional calcium content, supporting nutritional enhancement initiatives and calcium-fortified product lines.

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Effervescent & Chewable Formulations

Used in effervescent tablets and chewable calcium supplement formats, where its solubility characteristics and mild taste profile contribute to palatable, easy-to-consume supplement products.

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Pediatric & Geriatric Nutrition

Used in nutritional formulations targeting populations with specific calcium needs, including paediatric and geriatric nutrition products, due to its good tolerability profile across different age groups.

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Cosmetic Applications

Used in certain cosmetic formulations as a calcium source and texturising agent, contributing functional properties to specific personal care product types.

Technical Specifications

Calcium Gluconate — Key Properties

Chemical FormulaC12H22CaO14
CAS Number299-28-5
Molecular Weight430.37 g/mol
AppearanceWhite crystalline powder/granules
Purity99%+ (Food / Pharma Grade)
Melting PointDecomposes above 120°C (loses water of crystallisation)
Density / Bulk DensityBulk density: 0.4–0.6 g/cm3
pH6.0 – 8.5 (5% solution)
Packaging Available25 kg bags
StorageStore in cool, dry place away from moisture. Non-hygroscopic and stable in normal storage conditions. Shelf life 36 months.

Why Source Calcium Gluconate from Polychem Industries?

  • Food Grade and Pharma Grade available with full documentation
  • Pharma Grade meets USP / BP / IP specifications for injectable use
  • FSSAI compliant Food Grade supply with Certificate of Analysis
  • Gentle gastrointestinal tolerance compared to other calcium salts
  • Reliable bulk supply for supplement and pharmaceutical manufacturers
  • Export documentation experience for international shipments

Frequently Asked Questions

Why is Calcium Gluconate often preferred over other calcium salts for supplements?
Calcium Gluconate is often preferred because it tends to cause less gastrointestinal irritation compared to some other calcium salts, making it suitable for individuals with sensitive digestive systems. While it has a lower elemental calcium content per gram compared to calcium carbonate, its gentler tolerability profile makes it a popular choice in many supplement formulations, particularly for those requiring frequent or higher-volume calcium supplementation.
What is Calcium Gluconate used for in emergency medicine?
Pharma Grade Calcium Gluconate administered intravenously is used in emergency medicine for the rapid treatment of severe hypocalcaemia, to manage cardiac effects of hyperkalaemia (high potassium), and as an antidote for hydrofluoric acid burns and certain cases of magnesium sulphate overdose, where rapid calcium replacement can be life-saving.
What is the difference between Calcium Gluconate and Calcium Carbonate?
Calcium Carbonate has a higher elemental calcium content (approximately 40% calcium by weight) compared to Calcium Gluconate (approximately 9% calcium by weight), meaning more Calcium Gluconate is needed to deliver an equivalent calcium dose. However, Calcium Gluconate is generally better tolerated and requires less stomach acid for absorption, making it preferred in certain supplement formulations and especially in pharmaceutical injectable applications where Calcium Carbonate is not suitable.
Do you export Calcium Gluconate outside India?
Yes. We export to Bangladesh, Sri Lanka, Nepal, Bhutan, and South Africa with full export documentation. Contact us for export pricing and lead times.

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